TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer
نویسندگان
چکیده
منابع مشابه
The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer.
The tumor suppressor gene in lung cancer (TSLC1) encodes a membrane glycoprotein containing extensive homology in the extracellular domain with the immunoglobulin-superfamily cell adhesion molecules. The intracellular cytoplasmic domain (CT) contains a protein 4.1 (FERM) binding motif, and a PDZ-interacting motif. Expression of TSLC1 is silenced in non-small cell lung cancer and in other cancer...
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2001
ISSN: 1061-4036,1546-1718
DOI: 10.1038/86934